And independent cinema was dominated by the Europeans. Haroun had his first feature Bye Bye Africa, included in IFFK competition in 1999..“Ours is a competition for discovery, both of talents and countries,” says Ms Paul. But there was a whole lot of amazing stuff that was happening in the poorer parts of the world, in Latin America, Africa, Asia,” she adds. Venice and Cannes discovered him much later.Farhadi and Haroun would have made it big without IFFK — theirs is the kind of incandescence that can never be missed. And then, with A Separation, it PVC Smoothbore Anesthesia Circuit became a seemingly unending conquest — Cannes, Golden Globes, the Oscars, Venice, Berlin, Brisbane. But both had their first big triumphs at the IFFK. It was a Marxist government in power at the time, in 1999, but the Congress governments that came later did nothing to tamper with the festival’s combative instinct. Therefore, the selection into the IFFK competition is also a function of politics. His international breakthrough came only three years later, when About Elly won him the Silver Bear for best direction at Berlin 2009.

“Our strategy for selection of films for the competition category is founded on the very political philosophy of Kerala,” says Bina Paul, the longest-serving artistic director of IFFK.“When the IFFK competition section began in 1999, all distribution channels were controlled by Hollywood. They both have won big at Cannes, Venice and Berlin. Its competition section, it was then decided, will feature only third-world films. Big names are not invited and most of the winners over the years have been generally obscure. There is not a single mention of the International Film Festival of Kerala (IFFK) in the pages devoted to two of the most celebrated modern masters: Asghar Farhadi of *** (pictured) and Mahamat Saleh Haroun of Chad. For instance, the Mexican filmmaker Enrique Rivero, whose debut film Parque Via won in 2008, did not have a Wikipedia page until he made his much-celebrated third feature Pozoamargo — a full six years later.

“Last year, for instance, a competent Israeli film by a debut filmmaker was rejected because of the ferocious anti-Palestine sentiment it had demonstrated,” a member who was part of the jury at IFFK reveals. But the fact that they were recognised by IFFK long before the world took notice speaks something about this film festival’s unique culture. The festival’s curators have always demonstrated the monkish detachment of a talent scout. The film was celebrated at IFFK but did not win. In 2002, when he continued to be unknown even in his landlocked north African country, his second film, Abouna (Our Father), was picked for the IFFK and Haroun walked away with the ‘Suvarna Chakoram’ (Golden Pheasant) for the best film.Free-to-read Wikipedia can be very unkind.IFFK took up cudgels on their behalf. Both are reigning A-listers, auteurs to look out for at the European film festival circuit. The film won Farhadi the ‘Rajatha Chakoram’ (Silver Pheasant) for best direction.In 2006, when Farhadi’s name had not yet sailed East from ***, IFFK had included his third feature, Fireworks Wednesday, in its competition section. The philosophy she’s alluding to, in simple terms, means the fight for the underprivileged

Brawn suggested some races, such as China, could also be condensed into two days.Minimum eight racesBrawn said there was no point starting the season unless it could be kept going, with eight races the minimum necessary for a viable championship.“That’s not great, but I think it’s still better than no racing at all.“We could have a very enclosed environment where the teams come in on charters, we channel them into the circuit, we make sure everyone’s tested, cleared, there’s no risk to anyone and we have a race without spectators,” he added. So if you wanted a drop dead point it would be October,” he said when asked about a deadline...“At the moment we’re looking at the logistics of a closed race, how would we get the people there, how would we protect them, how would we make it safe, who would we allow into the paddock,” he said.

August break brought forwardFormula One has brought forward and extended its August break from March through to May to clear the European summer for a rescheduled calendar that could see races on successive weekends and into the New Year..London: Formula One is considering holding closed races without spectators, most likely at European circuits, once the season is able to start after being stalled by the new coronavirus pandemic.”Last month’s Bahrain Tracheotomy Filter Suppliers Grand Prix was due to be held without spectators, a first for the sport, before it had to be postponed.and that’s being explored, could we stray into January to finish the season.“Every permutation is being discussed.Formula One’s motorsport managing director Ross Brawn told a Sky Sports television ‘vodcast’ that a season of anywhere between eight and 19 races could still be possible.

Brawn said safety and travel were big issues and a European start was most likely even if much of the continent is currently in lockdown with movement restricted as countries fight to contain the virus.“But then there’s always the possibility we could run into next year.The Australian opener on March 15 was cancelled and every race up to the French Grand Prix on June 28 has been postponed so far.”Le Castellet, the French Grand Prix venue, is situated on a plateau in the south with its own airstrip, luxury hotel and few access roads..Circuits which fit the bill“I think we have to remember there’s millions of people that follow the sport sat at home.Austria’s Red Bull Ring is also a rural circuit while the British Grand Prix circuit at Silverstone is a short drive from seven of the 10 teams’ headquarters.“We could achieve eight races by starting in October.to be able to put on a sport and entertain people would be a huge bonus with this crisis we have.”“If we were to start at the beginning of July, we could do a 19-race season,” he added, outlining a scenario of multiple races on successive weekends.

Brawn suggested some races, such as China, could also be condensed into two days.Minimum eight racesBrawn said there was no point starting the season unless it could be kept going, with eight races the minimum necessary for a viable championship.“That’s not great, but I think it’s still better than no racing at all.“We could have a very enclosed environment where the teams come in on charters, we channel them into the circuit, we make sure everyone’s tested, cleared, there’s no risk to anyone and we have a race without spectators,” he added. So if you wanted a drop dead point it would be October,” he said when asked about a deadline...“At the moment we’re looking at the logistics of a closed race, how would we get the people there, how would we protect them, how would we make it safe, who would we allow into the paddock,” he said.

August break brought forwardFormula One has brought forward and extended its August break from March through to May to clear the European summer for a rescheduled calendar that could see races on successive weekends and into the New Year..London: Formula One is considering holding closed races without spectators, most likely at European circuits, once the season is able to start after being stalled by the new coronavirus pandemic.”Last month’s Bahrain Tracheotomy Filter Suppliers Grand Prix was due to be held without spectators, a first for the sport, before it had to be postponed.and that’s being explored, could we stray into January to finish the season.“Every permutation is being discussed.Formula One’s motorsport managing director Ross Brawn told a Sky Sports television ‘vodcast’ that a season of anywhere between eight and 19 races could still be possible.

Brawn said safety and travel were big issues and a European start was most likely even if much of the continent is currently in lockdown with movement restricted as countries fight to contain the virus.“But then there’s always the possibility we could run into next year.The Australian opener on March 15 was cancelled and every race up to the French Grand Prix on June 28 has been postponed so far.”Le Castellet, the French Grand Prix venue, is situated on a plateau in the south with its own airstrip, luxury hotel and few access roads..Circuits which fit the bill“I think we have to remember there’s millions of people that follow the sport sat at home.Austria’s Red Bull Ring is also a rural circuit while the British Grand Prix circuit at Silverstone is a short drive from seven of the 10 teams’ headquarters.“We could achieve eight races by starting in October.to be able to put on a sport and entertain people would be a huge bonus with this crisis we have.”“If we were to start at the beginning of July, we could do a 19-race season,” he added, outlining a scenario of multiple races on successive weekends.

But the condition, which involves the buildup of thick, sticky mucus in the lungs, is tied to more than 2,000 genetic mutations.This gave them an idea. The researchers then exposed the nasospheroids to various CFTR drugs to see what would happen. Guimbellot and Gentzsch learned how to grow nasospheroids from cells taken from the inside of the noses of cystic fibrosis patients. People develop CF because they do not have a functioning version of the CFTR gene.

The study is published in the Journal of Clinical Investigation Insight.Guimbellot was working with lead study author Martina Gentzsch on an unrelated research project when she noticed some funny little balls forming from cells taken from the inside of the nose.A team led by University of North Carolina researchers presented a simple test that aims to predict which treatment is most likely to work for each patient, an approach known as personalized or precision medicine.The results suggest growing nasospheroids from nasal samples could provide a quick screening method to determine how a patients Tracheotomy Filter cells react to different CFTR drugs. "We still have a long way to go to get a really optimized therapy for most cystic fibrosis patients, and the only way we can do that is to have a model like ours, where we can take cells from each individual patient and test them with each individual drug to find out which one is the best match."From a drug-design perspective, cystic fibrosis is an enormous challenge. "The spheroids form quickly in just a few days without much manipulation. The two scientists soon realized that the balls, which are called nasospheroids, were filled with fluid. Maybe these nasospheroids could help to study essential parts of the CF hydration problem.

It might even be more reliable from a screening standpoint because the drugs are able to interact directly with the right parts on the outside of the nasospheroids, rather than having to enter the spheroids as required with the rectal biopsy method. "It is a relatively simple procedure that doesn't require any anesthesia and uses a brush that غير مجاز مي باشدts a few dollars," said Gentzsch."Gentzsch said the testing approach could offer patients a welcome alternative to rectal biopsy. A person's specific combination of mutations affects both the severity of the disease and how well the patient responds to treatment. Fluid is at the heart of cystic fibrosis, since hydration of nasal and lung surfaces is what determines whether mucus is slippery or sticky."Any given drug may not be the drug that works best for a given patient, because there's so much variation from person to person," said researcher Jennifer Guimbellot..Washington: A team of researchers # has found a way to match each cystic fibrosis patient with their best individual treatment option.

But the condition, which involves the buildup of thick, sticky mucus in the lungs, is tied to more than 2,000 genetic mutations.This gave them an idea. The researchers then exposed the nasospheroids to various CFTR drugs to see what would happen. Guimbellot and Gentzsch learned how to grow nasospheroids from cells taken from the inside of the noses of cystic fibrosis patients. People develop CF because they do not have a functioning version of the CFTR gene.

The study is published in the Journal of Clinical Investigation Insight.Guimbellot was working with lead study author Martina Gentzsch on an unrelated research project when she noticed some funny little balls forming from cells taken from the inside of the nose.A team led by University of North Carolina researchers presented a simple test that aims to predict which treatment is most likely to work for each patient, an approach known as personalized or precision medicine.The results suggest growing nasospheroids from nasal samples could provide a quick screening method to determine how a patients Tracheotomy Filter cells react to different CFTR drugs. "We still have a long way to go to get a really optimized therapy for most cystic fibrosis patients, and the only way we can do that is to have a model like ours, where we can take cells from each individual patient and test them with each individual drug to find out which one is the best match."From a drug-design perspective, cystic fibrosis is an enormous challenge. "The spheroids form quickly in just a few days without much manipulation. The two scientists soon realized that the balls, which are called nasospheroids, were filled with fluid. Maybe these nasospheroids could help to study essential parts of the CF hydration problem.

It might even be more reliable from a screening standpoint because the drugs are able to interact directly with the right parts on the outside of the nasospheroids, rather than having to enter the spheroids as required with the rectal biopsy method. "It is a relatively simple procedure that doesn't require any anesthesia and uses a brush that غير مجاز مي باشدts a few dollars," said Gentzsch."Gentzsch said the testing approach could offer patients a welcome alternative to rectal biopsy. A person's specific combination of mutations affects both the severity of the disease and how well the patient responds to treatment. Fluid is at the heart of cystic fibrosis, since hydration of nasal and lung surfaces is what determines whether mucus is slippery or sticky."Any given drug may not be the drug that works best for a given patient, because there's so much variation from person to person," said researcher Jennifer Guimbellot..Washington: A team of researchers # has found a way to match each cystic fibrosis patient with their best individual treatment option.